Intrauterine insemination (IUI), also known as Artificial Insemination (AI), may be recommended for patients who have difficulties with intercourse, unexplained infertility, or minor sperm abnormalities. IUI is a fertility treatment that involves depositing sperm at the top of the uterus with a small catheter around the time of ovulation. The sperm is ‘prepared’ in the laboratory and concentrated so that more sperm of better-quality are in the final sample. The procedure is relatively simple and performed by a No.1 Fertility Specialist. Mild cramping may occur during and after the treatment.