Insemination

There are generally 2 different types of inseminations that can be used to fertilise the egg. One is "natural" IVF, then other is ICSI.

Natural/conventional IVF

"Natural" IVF is when we inseminate the egg surrounded with their support cells with thousands of sperm that have been prepared by the laboratory. This means that the sperm have to travel through the support cells, adhere and bind to the shell of the egg called the zona pellucida and then bind and fuse with the membrane of the egg. The sperm then needs to initiate a cascade of reactions for the egg to fertilise. All this means the sperm needs to be mature and have everything it needs to get through all the stages in the fertilisation process, so a form of natural sperm selection occurs with only the fittest sperm able to fertilise the egg.

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